› 3r1c

X-ray diffraction
2.05Å resolution

Crystal structure of GCGGCGGC duplex

Released:
DOI: 10.2210/pdb3r1c/pdb
PDB entry 3r1c coloured by chain, front view.
PDB entry 3r1c coloured by chain, side view.
PDB entry 3r1c coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome.
Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W
Nucleic Acids Res 39 7308-15 (2011)
PMID: 21596781

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196723 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (5'-R(*GP*CP*GP*GP*CP*GP*GP*C)-3') Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j
Length: 8 nucleotides
Theoretical weight: 2.6 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand SO4 7 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P1
Unit cell:
a: 39.697Å b: 76.891Å c: 85.398Å
α: 89.98° β: 88.61° γ: 77.29°
R-values:
R R work R free
0.218 0.216 0.257
Expression system: Not provided

Quick links

Citations

11 review citations

MBNL proteins and their target RNAs, interaction and splicing regulation.
Konieczny et al. (2014)
10 more

6 mentions without citation

Structural studies of CNG repeats.
Kiliszek et al. (2014)
5 more