› 3r1e

X-ray diffraction
0.97Å resolution

Crystal structure of GC(8BrG)GCGGC duplex

Released:
DOI: 10.2210/pdb3r1e/pdb
PDB entry 3r1e coloured by chain, front view.
PDB entry 3r1e coloured by chain, side view.
PDB entry 3r1e coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome.
Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W
Nucleic Acids Res 39 7308-15 (2011)
PMID: 21596781

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196725 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (5'-R(*GP*CP*(GRB)P*GP*CP*GP*GP*C)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 8 nucleotides
Theoretical weight: 2.68 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand GOL 1 x GOL
Ligand CA 2 x CA
Ligand BR 2 x BR
1 modified residue:
Ligand GRB 2 x GRB

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2
Unit cell:
a: 50.666Å b: 22.538Å c: 44.183Å
α: 90° β: 117.82° γ: 90°
R-values:
R R work R free
0.137 0.137 not available
Expression system: Not provided

Quick links

Citations

11 review citations

Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders.
Cleary et al. (2014)
10 more

4 mentions without citation

Structural studies of CNG repeats.
Kiliszek et al. (2014)
3 more