Function and Biology Details
Reaction catalysed:
4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA
Sequence domains:
- Ribosomal RNA adenine methyltransferase KsgA/Erm
- GTP binding domain
- GTPase Era
- Ribosomal RNA adenine dimethylase
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- K Homology domain, type 2
- Era-type guanine nucleotide-binding (G) domain
- P-loop containing nucleoside triphosphate hydrolase
6 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130531 (preferred)
Entry contents:
2 distinct polypeptide molecules
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (3 distinct):
GTPase Era
Molecule details ›
Chain: A
Length: 307 amino acids
Theoretical weight: 34.77 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 307 amino acids
Theoretical weight: 34.77 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
- Canonical:
O67800 (Residues: 1-301; Coverage: 100%)
Sequence domains:
Structure domains:
Ribosomal RNA small subunit methyltransferase A
Molecule details ›
Chain: B
Length: 248 amino acids
Theoretical weight: 28.4 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
Sequence domains: Ribosomal RNA adenine dimethylase
Structure domains:
Length: 248 amino acids
Theoretical weight: 28.4 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
- Canonical: O67680 (Residues: 1-248; Coverage: 100%)
Sequence domains: Ribosomal RNA adenine dimethylase
Structure domains:
