3rif

X-ray diffraction
3.34Å resolution

C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and glutamate.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentadecamer (preferred)
PDBe Complex ID:
PDB-CPX-211643 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Avermectin-sensitive glutamate-gated chloride channel GluCl alpha Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 347 amino acids
Theoretical weight: 39.64 KDa
Source organism: Caenorhabditis elegans
Expression system: Spodoptera frugiperda
Structure domains:
Mouse monoclonal Fab fragment, heavy chain Chains: F, G, H, I, J
Molecule details ›
Chains: F, G, H, I, J
Length: 221 amino acids
Theoretical weight: 23.92 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins
Mouse monoclonal Fab fragment, light chain Chains: K, L, M, N, O
Molecule details ›
Chains: K, L, M, N, O
Length: 210 amino acids
Theoretical weight: 22.62 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P43212
Unit cell:
a: 155.442Å b: 155.442Å c: 575.354Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.248 0.271
Expression systems:
  • Spodoptera frugiperda
  • Not provided