3rru

X-ray diffraction
3Å resolution

X-ray crystal structure of the VHS domain of human TOM1-like protein, Northeast Structural Genomics Consortium Target HR3050E

Released:
Source organism: Homo sapiens
Entry authors: Forouhar F, Lew S, Seetharaman J, Wang H, Ciccosanti C, Patel D, Acton TB, Xiao R, Everett JK, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131095 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TOM1-like protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 17.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75674 (Residues: 9-150; Coverage: 30%)
Gene names: SRCASM, TOM1L1
Sequence domains: VHS domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P3112
Unit cell:
a: 122.047Å b: 122.047Å c: 55.095Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.227 0.252
Expression system: Escherichia coli BL21(DE3)