› 3rwg

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-177756 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 32.03 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GJ77 (Residues: 24-299; Coverage: 80%)
Gene name: MHCI-B
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.79 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6V7J5 (Residues: 21-119; Coverage: 100%)
Gene name: B2M
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Protein Nef Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 1.09 KDa
Source organism: Simian immunodeficiency virus
Expression system: Not provided
UniProt:
  • Canonical: Q5QGG3 (Residues: 195-203; Coverage: 3%)
Gene name: nef

Ligands and Environments

3 bound ligands:
Ligand XPE 1 x XPE
Ligand NA 1 x NA
Ligand PEG 2 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P2
Unit cell:
a: 68.018Å b: 44.419Å c: 79.517Å
α: 90° β: 96.33° γ: 90°
R-values:
R R work R free
0.193 0.19 0.237
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

3 review citations

Nonhuman primate models for HIV/AIDS vaccine development.
Sui et al. (2013)
2 more

1 mention without citation

Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex.
Morita et al. (2016)