› 3s51

X-ray diffraction
3.3Å resolution

Structure of FANCI

Released:
DOI: 10.2210/pdb3s51/pdb
PDB entry 3s51 coloured by chain, front view.
PDB entry 3s51 coloured by chain, side view.
PDB entry 3s51 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.
Joo W, Xu G, Persky NS, Smogorzewska A, Rudge DG, Buzovetsky O, Elledge SJ, Pavletich NP
Science 333 312-6 (2011)
PMID: 21764741

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-185065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fanconi anemia group I protein homolog Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1308 amino acids
Theoretical weight: 147.12 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8K368 (Residues: 1-1302; Coverage: 98%)
Gene name: Fanci
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P1
Unit cell:
a: 114.7Å b: 136.5Å c: 149.7Å
α: 115.9° β: 106° γ: 95°
R-values:
R R work R free
0.259 0.259 0.278
Expression system: Spodoptera frugiperda

Quick links

Citations

34 review citations

The ubiquitin code.
Komander et al. (2012)
33 more

3 mentions without citation

Conformational variation in structures of classical and non-classical MHCII proteins and functional implications.
Painter et al. (2012)
2 more