› 3s5r

X-ray diffraction
2.6Å resolution

Crystal structure of a putative transcriptional regulator of the TETR family (SYN_02108) from Syntrophus aciditrophicus at 2.60 A resolution

Released:
DOI: 10.2210/pdb3s5r/pdb
PDB entry 3s5r coloured by chain, front view.
PDB entry 3s5r coloured by chain, side view.
PDB entry 3s5r coloured by chain, top view.
Source organism: Syntrophus aciditrophicus SB
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173710 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 216 amino acids
Theoretical weight: 24.43 KDa
Source organism: Syntrophus aciditrophicus SB
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2LS68 (Residues: 1-215; Coverage: 100%)
Gene name: SYN_02108
Sequence domains: Bacterial regulatory proteins, tetR family
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

2 bound ligands:
Ligand PEG 3 x PEG
Ligand EDO 2 x EDO
1 modified residue:
Ligand MSE 22 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: C2221
Unit cell:
a: 74.433Å b: 110.721Å c: 126.03Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.243 0.255
Expression system: Escherichia coli

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