› 3s63

X-ray diffraction
2.7Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124758 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Saposin B-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 13.57 KDa
Source organism: Necator americanus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: H2L2M0 (Residues: 1-117; Coverage: 100%)
Structure domains: Saposin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P6522
Unit cell:
a: 85.433Å b: 85.433Å c: 113.452Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.184 0.245
Expression system: Komagataella pastoris

Quick links

Citations

1 review citation

Structural features of many circular and leaderless bacteriocins are similar to those in saposins and saposin-like peptides.
Towle et al. (2017)
6 other articles

1 mention without citation

Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm.
Willis et al. (2011)