› 3s7x

X-ray diffraction
2.9Å resolution

Unassembled Washington University Polyomavirus VP1 Pentamer R198K Mutant

Released:
DOI: 10.2210/pdb3s7x/pdb
PDB entry 3s7x coloured by chain, front view.
PDB entry 3s7x coloured by chain, side view.
PDB entry 3s7x coloured by chain, top view.
Source organism: WU Polyomavirus
Primary publication:
Structures of the major capsid proteins of the human Karolinska Institutet and Washington University polyomaviruses.
Neu U, Wang J, Macejak D, Garcea RL, Stehle T
J Virol 85 7384-92 (2011)
PMID: 21543504

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107605 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major capsid protein VP1 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 267 amino acids
Theoretical weight: 29.02 KDa
Source organism: WU Polyomavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: A5HBD5 (Residues: 34-296; Coverage: 71%)
Sequence domains: Polyomavirus coat protein
Structure domains: Capsid protein VP1,Polyomavirus

Ligands and Environments

3 bound ligands:
Ligand GOL 5 x GOL
Ligand CL 5 x CL
Ligand NA 5 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P43212
Unit cell:
a: 166.2Å b: 166.2Å c: 127.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.234 0.253
Expression system: Escherichia coli

Quick links

Citations

5 review citations

A cornucopia of human polyomaviruses.
DeCaprio et al. (2013)
4 more

4 mentions without citation

Identification of Two Novel Members of the Tentative Genus Wukipolyomavirus in Wild Rodents.
Nainys et al. (2015)
3 more