› 3s98

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147890 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon alpha/beta receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 306 amino acids
Theoretical weight: 35.64 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P17181 (Residues: 30-332; Coverage: 57%)
Gene names: IFNAR, IFNAR1
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P212121
Unit cell:
a: 47.09Å b: 86.18Å c: 91.34Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.234
Expression system: Trichoplusia ni

Quick links

Citations

74 review citations

JAK/STAT signaling in hematological malignancies.
Vainchenker et al. (2013)
73 more

10 mentions without citation

The molecular basis for differential type I interferon signaling.
Schreiber G. (2017)
9 more