› 3saj

X-ray diffraction
2.5Å resolution

Crystal Structure of glutamate receptor GluA1 Amino Terminal Domain

Released:
DOI: 10.2210/pdb3saj/pdb
PDB entry 3saj coloured by chain, front view.
PDB entry 3saj coloured by chain, side view.
PDB entry 3saj coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structure of the glutamate receptor GluA1 N-terminal domain.
Yao G, Zong Y, Gu S, Zhou J, Xu H, Mathews II, Jin R
Biochem J 438 255-63 (2011)
PMID: 21639859

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148597 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Glutamate receptor 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 384 amino acids
Theoretical weight: 44.21 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P19490 (Residues: 22-392; Coverage: 42%)
Gene names: GluA1, Glur1, Gria1
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
1 bound ligand:
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 92.586Å b: 94.421Å c: 186.367Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.218 0.286

Quick links

Citations

5 review citations

Functional insights from glutamate receptor ion channel structures.
Kumar et al. (2013)
4 more

6 mentions without citation

Emerging models of glutamate receptor ion channel structure and function.
Mayer ML. (2011)
5 more