3sq3

X-ray diffraction
2.5Å resolution

Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase H182A Mutant

Released:
Model geometry
Fit model/data

Function and Biology Details

Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
PDBe Complex ID:
PDB-CPX-153609 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosyl-DNA phosphodiesterase 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 470 amino acids
Theoretical weight: 53.98 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P38319 (Residues: 79-539; Coverage: 85%)
Gene names: TDP1, YBR1520, YBR223C
Sequence domains: Tyrosyl-DNA phosphodiesterase
Structure domains: Endonuclease Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P1
Unit cell:
a: 64.148Å b: 81.786Å c: 98.585Å
α: 86.92° β: 85.53° γ: 67.1°
R-values:
R R work R free
0.206 0.205 0.231
Expression system: Escherichia coli BL21(DE3)

PDB-REDO