› 3sy7

X-ray diffraction
2.15Å resolution

Improved crystal structure of Pseudomonas aeruginosa OprD

Released:
DOI: 10.2210/pdb3sy7/pdb
PDB entry 3sy7 coloured by chain, front view.
PDB entry 3sy7 coloured by chain, side view.
PDB entry 3sy7 coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Substrate specificity within a family of outer membrane carboxylate channels.
Eren E, Vijayaraghavan J, Liu J, Cheneke BR, Touw DS, Lepore BW, Indic M, Movileanu L, van den Berg B
PLoS Biol 10 e1001242 (2012)
PMID: 22272184

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Porin D Chain: A
Molecule details ›
Chain: A
Length: 428 amino acids
Theoretical weight: 46.95 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: P32722 (Residues: 24-443; Coverage: 100%)
Gene names: PA0958, oprD
Sequence domains: outer membrane porin, OprD family
Structure domains: Porin

Ligands and Environments

1 bound ligand:
Ligand C8E 8 x C8E
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2
Unit cell:
a: 136.408Å b: 103.892Å c: 47.544Å
α: 90° β: 107.68° γ: 90°
R-values:
R R work R free
0.197 0.196 0.226
Expression system: Escherichia coli

Quick links

Citations

11 review citations

The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.
Li et al. (2015)
10 more

11 mentions without citation

Gating of β-Barrel Protein Pores, Porins, and Channels: An Old Problem with New Facets.
Mayse et al. (2023)
10 more