Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-105334 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
HLA class II histocompatibility antigen, DR alpha chain
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 182 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P01903 (Residues: 26-207; Coverage: 80%)
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DRB1 beta chain
Molecule details ›
Chain: B
Length: 221 amino acids
Theoretical weight: 25.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 221 amino acids
Theoretical weight: 25.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P01911 (Residues: 30-221; Coverage: 81%)
Sequence domains:
Structure domains:
T cell receptor alpha chain constant
T cell receptor beta constant 2
T-cell surface glycoprotein CD4
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 23-ID-B
Spacegroup:
P43212
Expression systems:
- Escherichia coli BL21(DE3)
- Spodoptera frugiperda
