› 3t24

X-ray diffraction
2.4Å resolution

Crystal structure of Pseudomonas aeruginosa OpdQ

Released:
DOI: 10.2210/pdb3t24/pdb
PDB entry 3t24 coloured by chain, front view.
PDB entry 3t24 coloured by chain, side view.
PDB entry 3t24 coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Substrate specificity within a family of outer membrane carboxylate channels.
Eren E, Vijayaraghavan J, Liu J, Cheneke BR, Touw DS, Lepore BW, Indic M, Movileanu L, van den Berg B
PLoS Biol 10 e1001242 (2012)
PMID: 22272184

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-191193 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable porin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 401 amino acids
Theoretical weight: 45.02 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HZH0 (Residues: 26-421; Coverage: 94%)
Gene name: PA3038
Sequence domains: outer membrane porin, OprD family
Structure domains: Porin

Ligands and Environments

2 bound ligands:
Ligand SO4 12 x SO4
Ligand C8E 12 x C8E
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P1
Unit cell:
a: 64.722Å b: 78.464Å c: 97.519Å
α: 77.76° β: 81.5° γ: 70.04°
R-values:
R R work R free
0.204 0.203 0.242
Expression system: Escherichia coli

Quick links

Citations

12 review citations

The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.
Li et al. (2015)
11 more

3 mentions without citation

Multiscale Simulations of Biological Membranes: The Challenge To Understand Biological Phenomena in a Living Substance.
Enkavi et al. (2019)
2 more