Function and Biology Details
Reaction catalysed:
Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Dipeptidyl peptidase 3 and peptide (preferred)
PDBe Complex ID:
PDB-CPX-164065 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Dipeptidyl peptidase 3
Molecule details ›
Chains: A, B
Length: 726 amino acids
Theoretical weight: 81.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Peptidase family M49
Structure domains:
Length: 726 amino acids
Theoretical weight: 81.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9NY33 (Residues: 1-726; Coverage: 99%)
Sequence domains: Peptidase family M49
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-4
Spacegroup:
P21
Expression systems:
- Escherichia coli
- Not provided
