› 3t95

X-ray diffraction
1.75Å resolution

Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2

Released:
DOI: 10.2210/pdb3t95/pdb
PDB entry 3t95 coloured by chain, front view.
PDB entry 3t95 coloured by chain, side view.
PDB entry 3t95 coloured by chain, top view.
Source organism: Yersinia pestis CO92
Primary publication:
The structure of LsrB from Yersinia pestis complexed with autoinducer-2.
Kavanaugh JS, Gakhar L, Horswill AR
Acta Crystallogr Sect F Struct Biol Cryst Commun 67 1501-5 (2011)
PMID: 22139152

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181090 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Autoinducer 2-binding protein LsrB Chain: A
Molecule details ›
Chain: A
Length: 335 amino acids
Theoretical weight: 36.35 KDa
Source organism: Yersinia pestis CO92
Expression system: Escherichia coli
UniProt:
  • Canonical: Q74PW2 (Residues: 26-339; Coverage: 100%)
Gene names: YPO0409, YP_3772, lsrB, y3772
Sequence domains: Periplasmic binding protein domain
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand PAV 1 x PAV
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P212121
Unit cell:
a: 40.613Å b: 61.033Å c: 125.231Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.213
Expression system: Escherichia coli

Quick links

Citations

2 review citations

AI-2-mediated signalling in bacteria.
Pereira et al. (2013)
1 more

1 mention without citation

The structure of LsrB from Yersinia pestis complexed with autoinducer-2.
Kavanaugh et al. (2011)