› 3te3

X-ray diffraction
2.69Å resolution

Coiled-coil oligomerization domain of the polycystin transient receptor potential channel PKD2L1

Released:
DOI: 10.2210/pdb3te3/pdb
PDB entry 3te3 coloured by chain, front view.
PDB entry 3te3 coloured by chain, side view.
PDB entry 3te3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure and characterization of coiled-coil domain of the transient receptor potential channel PKD2L1.
Molland KL, Paul LN, Yernool DA
Biochim Biophys Acta 1824 413-21 (2012)
PMID: 22193359

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192800 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polycystin-2-like protein 1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 39 amino acids
Theoretical weight: 4.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9P0L9 (Residues: 699-737; Coverage: 5%)
Gene names: PKD2L, PKD2L1, PKDL, TRPP3
Sequence domains: Ferredoxin I 4Fe-4S cluster domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P6522
Unit cell:
a: 74.634Å b: 74.634Å c: 185.791Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.255 0.253 0.29
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Structural biology of TRP channels.
Hellmich et al. (2014)
2 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)