› 3tpd

X-ray diffraction
1.5Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150090 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase toxin HipA Chain: A
Molecule details ›
Chain: A
Length: 440 amino acids
Theoretical weight: 49.37 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P23874 (Residues: 1-440; Coverage: 100%)
Gene names: JW1500, b1507, hipA
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand CL 1 x CL
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21
Unit cell:
a: 48.48Å b: 84.06Å c: 50.06Å
α: 90° β: 90.13° γ: 90°
R-values:
R R work R free
0.22 0.213 0.248
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Formation, physiology, ecology, evolution and clinical importance of bacterial persisters.
Van den Bergh et al. (2017)
6 more

5 mentions without citation

Wake me when it's over - Bacterial toxin-antitoxin proteins and induced dormancy.
Coussens et al. (2016)
4 more