› 3tqj

X-ray diffraction
2Å resolution

Structure of the superoxide dismutase (Fe) (sodB) from Coxiella burnetii

Released:
DOI: 10.2210/pdb3tqj/pdb
PDB entry 3tqj coloured by chain, front view.
PDB entry 3tqj coloured by chain, side view.
PDB entry 3tqj coloured by chain, top view.
Source organism: Coxiella burnetii
Primary publication:
Structural genomics for drug design against the pathogen Coxiella burnetii.
Franklin MC, Cheung J, Rudolph MJ, Burshteyn F, Cassidy M, Gary E, Hillerich B, Yao ZK, Carlier PR, Totrov M, Love JD
Proteins 83 2124-36 (2015)
PMID: 26033498

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148688 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Fe] Chains: A, B
Molecule details ›
Chains: A, B
Length: 210 amino acids
Theoretical weight: 24.54 KDa
Source organism: Coxiella burnetii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P19685 (Residues: 1-193; Coverage: 100%)
Gene names: CBU_1708, sodB
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand FE2 2 x FE2
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P212121
Unit cell:
a: 60.102Å b: 65.285Å c: 110.069Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.233 0.271
Expression system: Escherichia coli BL21(DE3)

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Citations

5 review citations

Laccases of prokaryotic origin: enzymes at the interface of protein science and protein technology.
Martins et al. (2015)
4 more

1 mention without citation

Antimicrobial, Antioxidant, and Antiproliferative Effects of Coronilla minima: An Unexplored Botanical Species.
Ferrante et al. (2020)