› 3tuo

X-ray diffraction
1.7Å resolution

Crystal structure of N-terminal domain of DNA-binding protein satb1

Released:
DOI: 10.2210/pdb3tuo/pdb
PDB entry 3tuo coloured by chain, front view.
PDB entry 3tuo coloured by chain, side view.
PDB entry 3tuo coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structural basis for the oligomerization of the N-terminal domain of SATB1.
Wang Z, Yang X, Chu X, Zhang J, Zhou H, Shen Y, Long J
Nucleic Acids Res 40 4193-202 (2012)
PMID: 22241778

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169635 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding protein SATB1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 105 amino acids
Theoretical weight: 11.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q01826 (Residues: 71-171; Coverage: 13%)
Gene name: SATB1
Sequence domains: Ubiquitin-like oligomerisation domain of SATB
Structure domains: SATB, ubiquitin-like oligomerisation domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 35.895Å b: 71.027Å c: 153.763Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.158 0.218
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Homeodomain proteins: an update.
Bürglin et al. (2016)
1 more

5 mentions without citation

SATB2: A versatile transcriptional regulator of craniofacial and skeleton development, neurogenesis and tumorigenesis, and its applications in regenerative medicine.
Huang et al. (2022)
4 more