› 3u0w

X-ray diffraction
2Å resolution

AD related murine antibody Fragment

Released:
DOI: 10.2210/pdb3u0w/pdb
PDB entry 3u0w coloured by chain, front view.
PDB entry 3u0w coloured by chain, side view.
PDB entry 3u0w coloured by chain, top view.
Source organisms:
Entry authors: Miles LA, Crespi GAN, Parker MW

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134474 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig heavy chain V region T601; Immunoglobulin heavy constant gamma 1 Chain: H
Molecule details ›
Chain: H
Length: 216 amino acids
Theoretical weight: 23.12 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: P01808 (Residues: 1-118; Coverage: 95%)
  • Canonical: P01857 (Residues: 1-103; Coverage: 26%)
Gene name: IGHG1
Sequence domains:
Structure domains: Immunoglobulins
Ig kappa chain V-V region HP 124E1; Immunoglobulin kappa constant Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.49 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: P01647 (Residues: 1-108; Coverage: 100%)
  • Canonical: P01834 (Residues: 2-107; Coverage: 99%)
Gene name: IGKC
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P212121
Unit cell:
a: 64.047Å b: 81.292Å c: 108.474Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.235
Expression system: Homo sapiens

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