› 3u4z

X-ray diffraction
2.3Å resolution

Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-B

Released:
DOI: 10.2210/pdb3u4z/pdb
PDB entry 3u4z coloured by chain, front view.
PDB entry 3u4z coloured by chain, side view.
PDB entry 3u4z coloured by chain, top view.
Source organism: Tetrahymena thermophila
Primary publication:
Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Zeng Z, Min B, Huang J, Hong K, Yang Y, Collins K, Lei M
Proc Natl Acad Sci U S A 108 20357-61 (2011)
PMID: 22143754

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-112349 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomeric repeat-binding subunit 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 109 amino acids
Theoretical weight: 13.02 KDa
Source organism: Tetrahymena thermophila
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D2CVN6 (Residues: 375-483; Coverage: 16%)
Gene names: TAP82, TEB1, TTHERM_00218760
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P21
Unit cell:
a: 34.551Å b: 65.841Å c: 57.845Å
α: 90° β: 100.01° γ: 90°
R-values:
R R work R free
0.225 0.22 0.266
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

Human telomerase: biogenesis, trafficking, recruitment, and activation.
Schmidt et al. (2015)
7 more

4 mentions without citation

Progress in Human and Tetrahymena Telomerase Structure Determination.
Chan et al. (2017)
3 more