› 3uxw

X-ray diffraction
2.27Å resolution

Crystal Structures of an A-T-hook/DNA complex

Released:
DOI: 10.2210/pdb3uxw/pdb
PDB entry 3uxw coloured by chain, front view.
PDB entry 3uxw coloured by chain, side view.
PDB entry 3uxw coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of a complex of DNA with one AT-hook of HMGA1.
Fonfría-Subirós E, Acosta-Reyes F, Saperas N, Pous J, Subirana JA, Campos JL
PLoS One 7 e37120 (2012)
PMID: 22615915

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-117011 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
A-T hook peptide Chains: K, L, M, N
Molecule details ›
Chains: K, L, M, N
Length: 10 amino acids
Theoretical weight: 1.13 KDa
Source organism: Synthetic construct
Expression system: Not provided
dodecamer DNA Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 12 nucleotides
Theoretical weight: 3.66 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: P21
Unit cell:
a: 49.143Å b: 66.855Å c: 50.052Å
α: 90° β: 111.4° γ: 90°
R-values:
R R work R free
0.223 0.219 0.277
Expression system: Not provided

Quick links

Citations

6 review citations

Do short, frequent DNA sequence motifs mould the epigenome?
Quante et al. (2016)
5 more

11 mentions without citation

Xenogeneic Silencing and Bacterial Genome Evolution: Mechanisms for DNA Recognition Imply Multifaceted Roles of Xenogeneic Silencers.
Duan et al. (2021)
10 more