› 3uyw

X-ray diffraction
1.9Å resolution

Crystal structures of globular head of 2009 pandemic H1N1 hemagglutinin

Released:
DOI: 10.2210/pdb3uyw/pdb
PDB entry 3uyw coloured by chain, front view.
PDB entry 3uyw coloured by chain, side view.
PDB entry 3uyw coloured by chain, top view.
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Primary publication:
Structural vaccinology: structure-based design of influenza A virus hemagglutinin subtype-specific subunit vaccines.
Xuan C, Shi Y, Qi J, Zhang W, Xiao H, Gao GF
Protein Cell 2 997-1005 (2011)
PMID: 22231357

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111237 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemagglutinin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 214 amino acids
Theoretical weight: 24.14 KDa
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: C3W5S1 (Residues: 65-278; Coverage: 38%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1

Ligands and Environments

1 bound ligand:
Ligand TAU 2 x TAU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P1
Unit cell:
a: 38.67Å b: 65.916Å c: 79.485Å
α: 94.46° β: 89.97° γ: 94.88°
R-values:
R R work R free
0.185 0.184 0.198
Expression system: Spodoptera frugiperda

Quick links

Citations

5 review citations

Immunogen design for HIV-1 and influenza.
Rathore et al. (2014)
4 more

1 mention without citation

Evolution of Indian Influenza A (H1N1) Hemagglutinin Strains: A Comparative Analysis of the Pandemic Californian HA Strain.
Pushan et al. (2023)