› 3v4c

X-ray diffraction
1.91Å resolution

Crystal structure of a semialdehyde dehydrogenase from Sinorhizobium meliloti 1021

Released:
DOI: 10.2210/pdb3v4c/pdb
PDB entry 3v4c coloured by chain, front view.
PDB entry 3v4c coloured by chain, side view.
PDB entry 3v4c coloured by chain, top view.
Source organism: Sinorhizobium meliloti 1021
Entry authors: Agarwal R, Chamala S, Evans B, Foti R, Gizzi A, Hillerich B, Kar A, LaFleur J, Seidel R, Villigas G, Zencheck W, Almo SC, Swaminathan S, New York Structural Genomics Research Consortium (NYSGRC)

Function and Biology Details

Reaction catalysed: 
An aldehyde + NADP(+) + H(2)O = a carboxylate + NADPH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187951 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldehyde dehydrogenase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 528 amino acids
Theoretical weight: 56.52 KDa
Source organism: Sinorhizobium meliloti 1021
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92WS7 (Residues: 1-505; Coverage: 100%)
Gene name: SM_b20262
Sequence domains: Aldehyde dehydrogenase family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PE4 1 x PE4
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2
Unit cell:
a: 187.197Å b: 46.079Å c: 117.404Å
α: 90° β: 104.76° γ: 90°
R-values:
R R work R free
0.174 0.171 0.225
Expression system: Escherichia coli BL21(DE3)

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