› 3v6p

X-ray diffraction
2.4Å resolution

Crystal structure of the DNA-binding domain of dHax3, a TAL effector

Released:
DOI: 10.2210/pdb3v6p/pdb
PDB entry 3v6p coloured by chain, front view.
PDB entry 3v6p coloured by chain, side view.
PDB entry 3v6p coloured by chain, top view.
Source organism: Xanthomonas
Primary publication:
Structural basis for sequence-specific recognition of DNA by TAL effectors.
Deng D, Yan C, Pan X, Mahfouz M, Wang J, Zhu JK, Shi Y, Yan N
Science 335 720-3 (2012)
PMID: 22223738

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164154 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dHax3 Chain: A
Molecule details ›
Chain: A
Length: 442 amino acids
Theoretical weight: 45.88 KDa
Source organism: Xanthomonas
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 74.762Å b: 95.507Å c: 153.207Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.211 0.264
Expression system: Escherichia coli

Quick links

Citations

130 review citations

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering.
Gaj et al. (2013)
129 more

10 mentions without citation

TAL effectors: function, structure, engineering and applications.
Mak et al. (2013)
9 more