3vfg

X-ray diffraction
1.65Å resolution

Crystal structure of monoclonal antibody 3F8 Fab fragment that binds to GD2 ganglioside

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213428 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
3F8 Light Chain Chain: L
Molecule details ›
Chain: L
Length: 211 amino acids
Theoretical weight: 23.25 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
3F8 Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 219 amino acids
Theoretical weight: 23.4 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 116.028Å b: 64.31Å c: 57.241Å
α: 90° β: 93.65° γ: 90°
R-values:
R R work R free
0.178 0.176 0.225
Expression system: Mus musculus