› 3vhs

X-ray diffraction
1.9Å resolution

Crystal structure of UBZ of human WRNIP1

Released:
DOI: 10.2210/pdb3vhs/pdb
PDB entry 3vhs coloured by chain, front view.
PDB entry 3vhs coloured by chain, side view.
PDB entry 3vhs coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1.
Suzuki N, Rohaim A, Kato R, Dikic I, Wakatsuki S, Kawasaki M
FEBS J 283 2004-17 (2016)
PMID: 27062441

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188747 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATPase WRNIP1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 29 amino acids
Theoretical weight: 3.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96S55 (Residues: 17-40; Coverage: 4%)
Gene names: WHIP, WRNIP1
Sequence domains: Werner helicase-interacting protein 1 ubiquitin-binding domain

Ligands and Environments

2 bound ligands:
Ligand ZN 2 x ZN
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: C2221
Unit cell:
a: 36.482Å b: 73.457Å c: 34.651Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.213 0.262
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Fundamental Characteristics of AAA+ Protein Family Structure and Function.
Miller et al. (2016)
2 more

2 mentions without citation

A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1.
Suzuki et al. (2016)
1 more