› 3vod

X-ray diffraction
2.6Å resolution

Crystal Structure of mutant MarR C80S from E.coli

Released:
DOI: 10.2210/pdb3vod/pdb
PDB entry 3vod coloured by chain, front view.
PDB entry 3vod coloured by chain, side view.
PDB entry 3vod coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
The multiple antibiotic resistance regulator MarR is a copper sensor in Escherichia coli.
Hao Z, Lou H, Zhu R, Zhu J, Zhang D, Zhao BS, Zeng S, Chen X, Chan J, He C, Chen PR
Nat Chem Biol 10 21-8 (2014)
PMID: 24185215

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150955 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Multiple antibiotic resistance protein MarR Chains: A, B
Molecule details ›
Chains: A, B
Length: 144 amino acids
Theoretical weight: 16.07 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P27245 (Residues: 1-144; Coverage: 100%)
Gene names: JW5248, b1530, cfxB, inaR, marR, soxQ
Sequence domains: MarR family
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P43212
Unit cell:
a: 62.162Å b: 62.162Å c: 131.466Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.257 0.256 0.281
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Unraveling the physiological complexities of antibiotic lethality.
Dwyer et al. (2015)
17 more

1 mention without citation

Domain-to-domain coupling in voltage-sensing phosphatase.
Sakata et al. (2017)