› 3vt3

X-ray diffraction
1.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Assembly name:
PDBe Complex ID:
PDB-CPX-146453 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vitamin D3 receptor Chain: A
Molecule details ›
Chain: A
Length: 271 amino acids
Theoretical weight: 30.55 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P13053 (Residues: 116-423; Coverage: 62%)
Gene names: Nr1i1, Vdr
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
COACTIVATOR PEPTIDE DRIP Chain: C
Molecule details ›
Chain: C
Length: 13 amino acids
Theoretical weight: 1.57 KDa
Source organism: Rattus norvegicus
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand VDX 1 x VDX
Ligand EDO 1 x EDO
Ligand FMT 2 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: C2
Unit cell:
a: 153.883Å b: 41.626Å c: 41.956Å
α: 90° β: 96.31° γ: 90°
R-values:
R R work R free
0.202 0.202 0.241
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

6 review citations

Vitamin D and Its Synthetic Analogs.
Maestro et al. (2019)
5 more

3 mentions without citation

Side-Chain Conformational Preferences Govern Protein-Protein Interactions.
Watkins et al. (2016)
2 more