› 3vts

X-ray diffraction
2.43Å resolution

Crystal structure of a three finger toxin from snake venom

Released:
DOI: 10.2210/pdb3vts/pdb
PDB entry 3vts coloured by chain, front view.
PDB entry 3vts coloured by chain, side view.
PDB entry 3vts coloured by chain, top view.
Source organism: Hemachatus haemachatus
Primary publication:
Identification and structural characterization of a new three-finger toxin hemachatoxin from Hemachatus haemachatus venom.
Girish VM, Kumar S, Joseph L, Jobichen C, Kini RM, Sivaraman J
PLoS One 7 e48112 (2012)
PMID: 23144733

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109821 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Three-finger hemachatoxin Chains: A, B
Molecule details ›
Chains: A, B
Length: 61 amino acids
Theoretical weight: 6.86 KDa
Source organism: Hemachatus haemachatus
UniProt:
  • Canonical: B3EWH9 (Residues: 1-61; Coverage: 100%)
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 49.718Å b: 50.057Å c: 57.813Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.232 0.281

Quick links

Citations

3 review citations

Snake Venom Peptides: Tools of Biodiscovery.
Munawar et al. (2018)
2 more

3 mentions without citation

Bioactive Molecules Derived from Snake Venoms with Therapeutic Potential for the Treatment of Thrombo-Cardiovascular Disorders Associated with COVID-19.
Chérifi et al. (2021)
2 more