› 3vuq

X-ray diffraction
2.05Å resolution

Crystal structure of TTHA0167, a transcriptional regulator, TetR/AcrR family from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb3vuq/pdb
PDB entry 3vuq coloured by chain, front view.
PDB entry 3vuq coloured by chain, side view.
PDB entry 3vuq coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Primary publication:
Structure and function of a TetR family transcriptional regulator, SbtR, from thermus thermophilus HB8.
Agari Y, Sakamoto K, Yutani K, Kuramitsu S, Shinkai A
Proteins 81 1166-78 (2013)
PMID: 23408580

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178227 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 187 amino acids
Theoretical weight: 21.37 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SLX6 (Residues: 3-189; Coverage: 99%)
Gene name: TTHA0167
Sequence domains:
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21
Unit cell:
a: 44.327Å b: 174.821Å c: 56.158Å
α: 90° β: 92.43° γ: 90°
R-values:
R R work R free
0.201 0.201 0.25
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The TetR family of regulators.
Cuthbertson et al. (2013)
1 more

1 mention without citation

Identification of Preferred DNA-Binding Sites for the Thermus thermophilus Transcriptional Regulator SbtR by the Combinatorial Approach REPSA.
Van Dyke et al. (2016)