› 3vx6

X-ray diffraction
2.6Å resolution

Crystal structure of Kluyveromyces marxianus Atg7NTD

Released:
DOI: 10.2210/pdb3vx6/pdb
PDB entry 3vx6 coloured by chain, front view.
PDB entry 3vx6 coloured by chain, side view.
PDB entry 3vx6 coloured by chain, top view.
Source organism: Kluyveromyces marxianus
Primary publication:
Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.
Yamaguchi M, Matoba K, Sawada R, Fujioka Y, Nakatogawa H, Yamamoto H, Kobashigawa Y, Hoshida H, Akada R, Ohsumi Y, Noda NN, Inagaki F
Nat Struct Mol Biol 19 1250-6 (2012)
PMID: 23142983

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-125803 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-like modifier-activating enzyme Atg7 N-terminal domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 283 amino acids
Theoretical weight: 32.21 KDa
Source organism: Kluyveromyces marxianus
Expression system: Escherichia coli
UniProt:
  • Canonical: L7MTK3 (Residues: 1-283; Coverage: 100%)
Sequence domains: Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P3121
Unit cell:
a: 118.908Å b: 118.908Å c: 45.05Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.224 0.268
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Historical landmarks of autophagy research.
Ohsumi Y. (2014)
11 more

1 mention without citation

Crystallographic Characterization of ATG Proteins and Their Interacting Partners.
Qiu et al. (2017)