› 3vzt

X-ray diffraction
2.3Å resolution

Crystal Structure of outer membrane protein PorB from Neisseria meningitidis

Released:
DOI: 10.2210/pdb3vzt/pdb
PDB entry 3vzt coloured by chain, front view.
PDB entry 3vzt coloured by chain, side view.
PDB entry 3vzt coloured by chain, top view.
Source organism: Neisseria meningitidis
Primary publication:
Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB.
Tanabe M, Nimigean CM, Iverson TM
Proc Natl Acad Sci U S A 107 6811-6 (2010)
PMID: 20351243

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177788 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein II Chain: X
Molecule details ›
Chain: X
Length: 355 amino acids
Theoretical weight: 38.18 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5RT80 (Residues: 1-322; Coverage: 100%)
Gene name: porB
Sequence domains: Gram-negative porin
Structure domains: Porin

Ligands and Environments

1 bound ligand:
Ligand CS 3 x CS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P63
Unit cell:
a: 83.052Å b: 83.052Å c: 106.371Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.214 0.26
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis.
Goh et al. (2012)
5 more

4 mentions without citation

Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition.
Kattner et al. (2014)
3 more