› 3vzu

X-ray diffraction
2.9Å resolution

Crystal Structure of outer membrane protein PorB from Neisseria meningitidis in complex with AMP-PNP

Released:
DOI: 10.2210/pdb3vzu/pdb
PDB entry 3vzu coloured by chain, front view.
PDB entry 3vzu coloured by chain, side view.
PDB entry 3vzu coloured by chain, top view.
Source organism: Neisseria meningitidis
Primary publication:
Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB.
Tanabe M, Nimigean CM, Iverson TM
Proc Natl Acad Sci U S A 107 6811-6 (2010)
PMID: 20351243

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125989 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein Chain: X
Molecule details ›
Chain: X
Length: 355 amino acids
Theoretical weight: 38.18 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
UniProt:
  • Canonical: M4GGR4 (Residues: 1-355; Coverage: 100%)
Sequence domains: Gram-negative porin
Structure domains: Porin

Ligands and Environments

1 bound ligand:
Ligand ANP 1 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P63
Unit cell:
a: 84.482Å b: 84.482Å c: 106.302Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.239 0.237 0.273
Expression system: Escherichia coli

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Citations

6 review citations

Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis.
Goh et al. (2012)
5 more