Function and Biology Details
Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Endonuclease 8-like 3 (preferred)
PDBe Complex ID:
PDB-CPX-185056 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endonuclease 8-like 3
Molecule details ›
Chain: A
Length: 287 amino acids
Theoretical weight: 31.85 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Formamidopyrimidine-DNA glycosylase H2TH domain
Structure domains:
Length: 287 amino acids
Theoretical weight: 31.85 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8K203 (Residues: 2-282; Coverage: 46%)
Sequence domains: Formamidopyrimidine-DNA glycosylase H2TH domain
Structure domains:
