› 3w3v

X-ray diffraction
3.2Å resolution

Crystal structure of Kap121p mutant D353K/E396K/D438K

Released:
DOI: 10.2210/pdb3w3v/pdb
Model geometry
Fit model/data
PDB entry 3w3v coloured by chain, front view.
PDB entry 3w3v coloured by chain, side view.
PDB entry 3w3v coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
Kobayashi J, Matsuura Y
J Mol Biol 425 1852-1868 (2013)
PMID: 23541588

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152266 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Importin subunit beta-3 Chain: A
Molecule details ›
Chain: A
Length: 1078 amino acids
Theoretical weight: 119.94 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P32337 (Residues: 1-1089; Coverage: 99%)
Gene names: KAP121, PSE1, YM9952.10C, YMR308C
Sequence domains:
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P21
Unit cell:
a: 77.79Å b: 122.31Å c: 84.67Å
α: 90° β: 116.08° γ: 90°
R-values:
R R work R free
0.205 0.203 0.252
Expression system: Escherichia coli

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Citations

6 review citations

The Structure of the Nuclear Pore Complex (An Update).
Lin et al. (2019)
5 more