› 3w9t

X-ray diffraction
2.9Å resolution

pore-forming CEL-III

Released:
DOI: 10.2210/pdb3w9t/pdb
PDB entry 3w9t coloured by chain, front view.
PDB entry 3w9t coloured by chain, side view.
PDB entry 3w9t coloured by chain, top view.
Source organism: Cucumaria echinata
Primary publication:
Hemolytic lectin CEL-III heptamer reveals its transmembrane pore-formation mechanism
Unno H, Goda S, Hatakeyama T
J. Biol. Chem. (2014)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183108 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galactose/N-acetylgalactosamine-binding lectin CEL-III Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 432 amino acids
Theoretical weight: 47.45 KDa
Source organism: Cucumaria echinata
UniProt:
  • Canonical: Q868M7 (Residues: 11-442; Coverage: 98%)
Gene name: cel3
Sequence domains: Ricin-type beta-trefoil lectin domain
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: FRU, GAL
Carbohydrate polymer
2 bound ligands:
Ligand CA 44 x CA
Ligand MG 14 x MG
1 modified residue:
Ligand PCA 7 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2
Unit cell:
a: 219.8Å b: 228.65Å c: 133.02Å
α: 90° β: 127.13° γ: 90°
R-values:
R R work R free
0.241 0.239 0.273

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