Function and Biology Details
Reaction catalysed:
Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179684 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Uracil-DNA glycosylase
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 26.07 KDa
Source organism: Staphylococcus aureus subsp. aureus MRSA252
Expression system: Escherichia coli
UniProt:
Sequence domains: Uracil DNA glycosylase superfamily
Structure domains: Uracil-DNA glycosylase-like domain
Length: 226 amino acids
Theoretical weight: 26.07 KDa
Source organism: Staphylococcus aureus subsp. aureus MRSA252
Expression system: Escherichia coli
UniProt:
- Canonical:
Q6GJ88 (Residues: 1-218; Coverage: 100%)
Sequence domains: Uracil DNA glycosylase superfamily
Structure domains: Uracil-DNA glycosylase-like domain
Uncharacterized protein
Molecule details ›
Chain: B
Length: 112 amino acids
Theoretical weight: 13.37 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
Structure domains: S. aureus uracil DNA glycosylase inhibitor
Length: 112 amino acids
Theoretical weight: 13.37 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
- Canonical: Q936H5 (Residues: 1-112; Coverage: 100%)
Structure domains: S. aureus uracil DNA glycosylase inhibitor
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSRRC BEAMLINE BL13B1
Spacegroup:
P212121
Expression system: Escherichia coli
