› 3wtd

X-ray diffraction
2.35Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189734 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein PAXX Chains: A, B
Molecule details ›
Chains: A, B
Length: 168 amino acids
Theoretical weight: 17.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BUH6 (Residues: 1-166; Coverage: 81%)
Gene names: C9orf142, PAXX, XLS
Sequence domains: PAXX, PAralog of XRCC4 and XLF, also called C9orf142

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P6522
Unit cell:
a: 91.948Å b: 91.948Å c: 153.162Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.193 0.229
Expression system: Escherichia coli

Quick links

Citations

73 review citations

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Blackford et al. (2017)
72 more

5 mentions without citation

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.
Ochi et al. (2015)
4 more