› 3wyr

X-ray diffraction
2.8Å resolution

Crystal structure of Killer cell immunoglobulin-like receptor 2DL4

Released:
DOI: 10.2210/pdb3wyr/pdb
PDB entry 3wyr coloured by chain, front view.
PDB entry 3wyr coloured by chain, side view.
PDB entry 3wyr coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.
Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J, Vivian JP
J Biol Chem 290 10460-71 (2015)
PMID: 25759384

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189249 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Killer cell immunoglobulin-like receptor 2DL4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 206 amino acids
Theoretical weight: 22.92 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q99706 (Residues: 24-218; Coverage: 55%)
Gene names: CD158D, KIR103AS, KIR2DL4
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P4212
Unit cell:
a: 87.836Å b: 87.836Å c: 105.996Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.211 0.243
Expression system: Homo sapiens

Quick links

Citations

14 review citations

Uterine Natural Killer Cells: Functional Distinctions and Influence on Pregnancy in Humans and Mice.
Gaynor et al. (2017)
13 more

3 mentions without citation

The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.
Moradi et al. (2015)
2 more