› 3zdo

X-ray diffraction
2.07Å resolution

Tetramerization domain of Measles virus phosphoprotein

Released:
DOI: 10.2210/pdb3zdo/pdb
PDB entry 3zdo coloured by chain, front view.
PDB entry 3zdo coloured by chain, side view.
PDB entry 3zdo coloured by chain, top view.
Source organism: Measles morbillivirus
Primary publication:
Structure of the tetramerization domain of measles virus phosphoprotein.
Communie G, Crépin T, Maurin D, Jensen MR, Blackledge M, Ruigrok RW
J Virol 87 7166-9 (2013)
PMID: 23576502

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182819 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoprotein Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 84 amino acids
Theoretical weight: 9.61 KDa
Source organism: Measles morbillivirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q83623 (Residues: 304-377; Coverage: 15%)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

1 bound ligand:
Ligand MRD 1 x MRD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P1
Unit cell:
a: 27.67Å b: 45.72Å c: 115.83Å
α: 91.42° β: 93.58° γ: 90.08°
R-values:
R R work R free
0.213 0.21 0.284
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

The paramyxovirus polymerase complex as a target for next-generation anti-paramyxovirus therapeutics.
Cox et al. (2015)
8 more

13 mentions without citation

Structure and organization of paramyxovirus particles.
Cox et al. (2017)
12 more