› 3zdp

X-ray diffraction
2.69Å resolution

R416A Monomeric nucleoprotein of influenza A virus

Released:
DOI: 10.2210/pdb3zdp/pdb
Model geometry
Fit model/data
PDB entry 3zdp coloured by chain, front view.
PDB entry 3zdp coloured by chain, side view.
PDB entry 3zdp coloured by chain, top view.
Source organism: Influenza A virus
Primary publication:
Monomeric nucleoprotein of influenza A virus.
Chenavas S, Estrozi LF, Slama-Schwok A, Delmas B, Di Primo C, Baudin F, Li X, Crépin T, Ruigrok RW
OpenAccess logo PLoS Pathog 9 e1003275 (2013)
PMID: 23555270

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147421 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 498 amino acids
Theoretical weight: 56.37 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P15682 (Residues: 1-498; Coverage: 100%)
Gene name: NP
Sequence domains: Influenza virus nucleoprotein

Ligands and Environments

1 bound ligand:
Ligand K 3 x K
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: C2221
Unit cell:
a: 165.42Å b: 285.44Å c: 118.31Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.25
Expression system: Escherichia coli BL21(DE3)

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Citations

16 review citations

Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis.
Te Velthuis et al. (2016)
15 more

11 mentions without citation

Influenza A Virus Nucleoprotein: A Highly Conserved Multi-Functional Viral Protein as a Hot Antiviral Drug Target.
Hu et al. (2017)
10 more