3zi1

X-ray diffraction
1.9Å resolution

Crystal structure of human glyoxalase domain-containing protein 4 (GLOD4)

Released:
Source organism: Homo sapiens
Entry authors: Oberholzer A, Kiyani W, Shrestha L, Vollmar M, Krojer T, Froese DS, Williams E, von Delft F, Burgess-Brown N, Arrowsmith CH, Edwards A, Bountra C, Yue WW

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-190767 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glyoxalase domain-containing protein 4 Chain: A
Molecule details ›
Chain: A
Length: 330 amino acids
Theoretical weight: 36.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HC38 (Residues: 1-287; Coverage: 87%)
Gene names: C17orf25, CGI-150, GLOD4, My027
Sequence domains:
Structure domains: 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Unit cell:
a: 119.291Å b: 42.918Å c: 68.103Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.167 0.165 0.204
Expression system: Escherichia coli BL21(DE3)