› 3ziv

X-ray diffraction
2.65Å resolution

Crystal Structure of Ancestral Thioredoxin Relative to last Archaea- Eukaryotes Common Ancestor (AECA) from the Precambrian Period

Released:
DOI: 10.2210/pdb3ziv/pdb
PDB entry 3ziv coloured by chain, front view.
PDB entry 3ziv coloured by chain, side view.
PDB entry 3ziv coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Conservation of protein structure over four billion years.
Ingles-Prieto A, Ibarra-Molero B, Delgado-Delgado A, Perez-Jimenez R, Fernandez JM, Gaucher EA, Sanchez-Ruiz JM, Gavira JA
Structure 21 1690-7 (2013)
PMID: 23932589

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164254 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AECA THIOREDOXIN Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 106 amino acids
Theoretical weight: 12.03 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 37.65Å b: 48.85Å c: 91.17Å
α: 90° β: 93.23° γ: 90°
R-values:
R R work R free
0.185 0.181 0.276
Expression system: Escherichia coli BL21(DE3)

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Citations

8 review citations

Computational methods in drug discovery.
Leelananda et al. (2016)
7 more

4 mentions without citation

Conservation of protein structure over four billion years.
Ingles-Prieto et al. (2013)
3 more