› 3zoz

X-ray diffraction
1.95Å resolution

The structure of human phosphoglycerate kinase with bound bromide, a stimulating anion.

Released:
DOI: 10.2210/pdb3zoz/pdb
PDB entry 3zoz coloured by chain, front view.
PDB entry 3zoz coloured by chain, side view.
PDB entry 3zoz coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Bowler MW

Function and Biology Details

Reaction catalysed: 
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132717 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoglycerate kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 417 amino acids
Theoretical weight: 44.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P00558 (Residues: 1-417; Coverage: 100%)
Gene names: MIG10, OK/SW-cl.110, PGK1, PGKA
Sequence domains: Phosphoglycerate kinase
Structure domains: Phosphoglycerate kinase, N-terminal domain

Ligands and Environments

5 bound ligands:
Ligand MG 1 x MG
Ligand BR 1 x BR
Ligand MGF 1 x MGF
Ligand 3PG 1 x 3PG
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 38.98Å b: 91.81Å c: 108.21Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 0.161 0.209
Expression system: Escherichia coli BL21

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