› 3zp1

X-ray diffraction
2.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179550 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Hemagglutinin Chain: E
Molecule details ›
Chain: E
Length: 326 amino acids
Theoretical weight: 37.03 KDa
Source organism: Influenza A virus
Expression system: Gallus gallus
UniProt:
  • Canonical: Q6DQ34 (Residues: 17-342; Coverage: 58%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin Chain: F
Molecule details ›
Chain: F
Length: 166 amino acids
Theoretical weight: 19.1 KDa
Source organism: Influenza A virus
Expression system: Gallus gallus
UniProt:
  • Canonical: Q6DQ34 (Residues: 347-512; Coverage: 29%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: GAL, SIA
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND
Spacegroup: R32
Unit cell:
a: 101.09Å b: 101.09Å c: 448.46Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.223 0.286
Expression system: Gallus gallus

Quick links

Citations

10 review citations

Role of receptor binding specificity in influenza A virus transmission and pathogenesis.
de Graaf et al. (2014)
9 more

1 mention without citation

Changes in the hemagglutinin of H5N1 viruses during human infection--influence on receptor binding.
Crusat et al. (2013)