› 3zql

X-ray diffraction
2.99Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117122 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
HTH tetR-type domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 267 amino acids
Theoretical weight: 30.24 KDa
Source organism: Streptomyces antibioticus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9AMH9 (Residues: 3-261; Coverage: 99%)
Gene names: sim16, simReg2
Sequence domains:
Structure domains:
5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*CP*CP*GP*TP*AP*DCP *GP*AP*A)-3' Chains: E, G
Molecule details ›
Chains: E, G
Length: 17 nucleotides
Theoretical weight: 5.19 KDa
Source organism: Streptomyces antibioticus
Expression system: Not provided
5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*GP*CP*GP*TP*AP*DCP *GP*AP*A)-3' Chains: F, H
Molecule details ›
Chains: F, H
Length: 17 nucleotides
Theoretical weight: 5.23 KDa
Source organism: Streptomyces antibioticus
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 85.788Å b: 112.613Å c: 163.725Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.21 0.251
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links

Citations

4 review citations

The TetR family of regulators.
Cuthbertson et al. (2013)
3 more

7 mentions without citation

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures.
Housseini B Issa et al. (2018)
6 more